The leg isn't exactly devoid of lethality, either. A shot to the thigh would likely kill whomever was shot, and, even if they live, they'll be maimed.
maybe... IF you hit the artery... small target compared to the rest of the meat mass in the leg. And even if you do... you can throw a tourniquet on to prevent the man from dying, and if help arrives soon enough and they can get some clamps on the Artery soon enough, they may even save his leg.
Shoot em in the torso and you're MUCH more likely to kill someone.
Arms are the only other good place to shoot someone with intent to wound and stop them instead of killing them.
Here's the thing.
You have a gun, in your home, ready to defend your self and your property
Here is an intruder... armed with, you come to find, a small hard pipe or knife.
You aim at him and tell them to leave now.
Instead they come toward you.
You have limited options at this point. You CANNOT allow them to reach you.
You can shoot center mass which will assuredly drop them, and most likely kill them
Or you can pop em in the leg or arm and call the police and hope for the best.
Typically, I would recommend for most people to always shoot center mass.
Myself? If I can avoid killing them, I will.