For the life of me, I can't comprehend why a PC gamer would go with a standard console-type controller. Won't you miss out on mapping the hotkeys? Having less than eight programmed hotkeys would drive me insane! To each his (or her) own, I guess. I use a mouse + a Razer Nostromo N52 gaming device. I've been using the Nostromo series since 2004 and I've never looked back at console controllers nor keyboards since the switch.
I use a specific gaming keyboard, Razer mouse and Nostromo gamepad, and a console type controller (in either 360 or keyboard emulation modes)...and, to be quite honest, where I found the controller to be great for Oblivion and Fallout/FNV, I only use either the keyboard or gamepad and mouse for Skyrim.
I don't know how anyone plays it using a PS3 or Xbox type controller...I found it shocking, and the hotkey issue in 360 mode was ridiculous.
If I was to use the controller, I would only use it in keyboard emulation mode, and I would re-map virtually everything to something more sensible...plus I would definitely sensitise the settings.
Edit: If you need an emulation programme for a controller, google 'Xpadder'. Best freeware I found some time back.