Vampire: The Masquerade - Bloodlines. A game like this would obviously be risky to remake. So risky I'd hesitate even to apply theoretical dream-logic to it, but I'd certainly love to see it. The original is a favorite and a classic considered by many to be one of the best games ever, and this is despite the fact that the game was badly, badly plagued with problems throughout development. It was released loaded with bugs and left-out content. It'd be awesome to be able to go back and let it be developed with a AAA budget and no development nightmares, and see how much better it could have been.