I don't mind homosixuality and/or heterosixuality being addressed in my game if it is done in a mature and serious manner. I don't want either addressed in a way as to be demeaning to anyone or there just to be there. If there is some point to be made and driven home, something to make one think about how we treat others who are different than ourselves or a message of tolerance of those we don't understand...then sure, go with it. But that is no different than having racial differences addressed in game. There needs to be a reason for it to come up.
After all, when I go out on a Friday night in real life, such things just don't routinely present themselves. While I may associate with different folks with different likes and dislikes when it comes to six or different races, we just don't have need for it to come up in conversation or to discuss one another's six life. I would hate for it to come up in a forced way as if it was included just to apease folks who want it there "just because". There must be a good reason for it to have come up at all.