Been up all night drinking coffee and it has not crashed once. Plays smooth but I hate the UI.......again (I mean really. How many times do we have to deal with a crappy UI before you guys get it!!?? Is it really that hard??). The only issue I have is with how the shadows look and the mouse sensitivity thing.

I've played 13 hours now. I've encountered few CTDs in the wilderness after long (over 3 hour) play sessions. No other issues. The game runs well on Ultra in 1080p, but I increased fps a bit by lowering MSAA from 8 to 4, and long distance LOD detail from Ultra to High. Specs in my sig, Win7 64bit.