I get my copy tomorrow...and to be honest after reading the onslaught of PC issue-related complaints...I'm absolutely terrified.

This forum can really get one's morale down...
Thats because:
1. The majority of forum users are thoose that complain, thoose that have no problems rather play the game then talk about it
2. You're probably attracted to complaint and whine threads...ignore them...either your game runs or it doesn't...if not...buy a new system
Oh and btw. would you please mind to not undress in front of a internet camera and use the screen as a avatar. Let's you look hilarious and childish, though you're probably trying to look sixy and attract male people^^
Ontopic:
No crashes, No bugs, No glitches after 15 hours of gameplay. I even figured out recently that I can max out all the graphical settings except shadows in 1600x900 resolution. Since I'm on XP, Skyrim runs in DX9 for me, and thus I can enjoy the whole potential even with a old system like mine:
Athlon 64 XP2 dual core 6000+ (2x~3.09Ghz)
Nvidia 9600 GT 512 RAM
3 GIG RAM at 1.066 Mhz
Windows XP SP3
Line6 UX1 sound station