On my Intel i5 2500k (no oc), 4gb 1333mhz ram and my XFX 6870 :
Falkreath: vanilla=42, r3=56, r4FPU=60, ,r4SSE2=60
Markarth: vanilla=32, r3=44, r4FPU=44, ,r4SSE2=48
Riften: vanilla=37, r3=50, r4FPU=53, ,r4SSE2=53
Solitude: vanilla=32, r3=49, r4FPU=53, ,r4SSE2=53
Witherun: vanilla=39, r3=60, r4FPU=60, ,r4SSE2=60
I'm constantly using r4 SSE2 to play since last 2 days. The only thing i've to report is....that run like a charm ! Played for over 3hours going everywhere, buying/selling stuffs, killing npc, doing quest and traveling around the world without ANY kind of problem. I repeat, i do normally 2 session of 3hours each of gameplay, the last 2 days with r4 SSE2 and never got a ctd. Will continue to test it. ALL OK till now

Thnx again Alexander !
E D I T :
PS: For all the guys still getting stuttering after 30mins/1hour of play, say bye bye to your "clutters" enhanced textures. As i tested it, mods that expand clutters textures will give that horrible stuttering everytime u exit from an house/shop/tavern ecc. Probably bcause the engine need to clear cache or ram or videoram, dunno exactly, and the clutters seems to be too "heavy".
Give it a try. Delete ur "clutters" folder from ur "Data\Textures\" and start to play like first time u did. No stutters anymore after 30mins/1hour of play.
Use mods as u want, but use brain and test them ALWAYS. Something wrong with ur last addon ? delete it.
