Mounted Combat, Better Follower AI, Werebears, Lycanthropy Perk Tree and Vampire Finishers are a must. Lycanthropy needs a Perk Tree far more than Vampirism does, due to the fact that Vampires still have access to 100% of their perks, while a transformed Lycanthrope has access to none of their perks.
Its a must for WereBears, i mean there supposed to be in Skyrim, one book explains that many people place wolfsbane? (i think) on there houses. its been asked by the community many times and its in the lore of the province.
Canis Root. The "On Lycanthropy" book from Daggerfall stated that the people of Skyrim rubbed Canis Root on the trees near their house to ward off Werebears; the most common Lycanthrope in Skyrim. In Bloodmoon however, there were some houses in the Skaal Village that had dried Wolvesbane hanging in them.