And funny you mention that. There's more people who like it than one's who don't. The people who post here are the minority, so... yeah.
I have a friend that had a similar story to mine in Whiterun, he didn't post here...

That's how I feel about dragons, frankly. So I expect that this won't be that big a deal to me when I eventually come across it.
Then again, maybe it'll be 100 times worse than what I'm expecting.
The Dragons are different though, while granted a dragon can kill guards it's not as fast as two master vampires can.
Also, through testing I've done with my friend we seem to have the "randomness' plotted out. The vampires will only appear at night, and seem to appear shortly after you enter the city (for the major cities at least) at the main gate. If you enter the city, wait around for a minute or two and no vampires have appeared it should be safe for you to continue on without worrying about anything. Although it may be possible that they can enter the city while you are zoning out of the tavern, I haven't come across it yet.
We haven't done any testing with the minor cities, so I am unaware of how those get attacked by vampires. I assume it is something similar, although I have no idea where they would spawn.
As i have said before i just ignore them like i ignore dragons because it gets to a point where you don't really care anymore.
Ah...apathy...